Eczema is a common inflammatory disease in which patients often present with a persistent and recurrent rash that is characterized by redness, edema, itching, and dryness, and may be accompanied by blistering, rupture, bleeding or oozing, crusting, and exfoliation. AIDS is an immune system deficiency disease, and patients can suffer from recurrent infections throughout the body due to immune deficiency. AIDS and eczema can be identified from four aspects: medical history, etiology, symptoms and signs and auxiliary examinations, as follows: 1. Medical history: AIDS patients usually have a history of unsafe sex, history of intravenous drug use, history of irregular blood transfusion, etc.; eczema may have a history of infection, endocrine and metabolic disorders, blood circulation disorders, and allergen exposure before the onset of eczema; 2. A variety of allergic factors, as well as the patient’s personal constitution is directly related, and whether there is a viral infection is usually irrelevant. AIDS is a common sexually transmitted disease caused by patients infected with HIV; 3, signs and symptoms: some patients with AIDS may have clinical symptoms similar to eczema at the same time, but not a single performance similar to eczema, but also accompanied by a variety of opportunistic infections, often seen with skin viral, fungal and bacterial infections. The situation, as well as the occurrence of tuberculosis, Pneumocystis jiroveci pneumonia, etc.; 4, examination: blood tests for HIV antibodies can clarify AIDS, is the most accurate means of identifying eczema and AIDS.