Vitiligo is a multifactorial skin disease, which is characterized by local or generalized pigment loss forming white patches, is an acquired limited or generalized skin pigmentation disorder, is a common skin disease affecting beauty, easy to diagnose and difficult to treat. The specific pathogenesis is not yet clear, and there are four possible autoimmune theories (generally accepted), neurohumoral factors, auto-cytotoxicity (increased susceptibility due to oxidative stress), and melanocyte self-destruction theory. The majority of scholars tend to use autoimmunity to explain, recent studies also show that vitiligo pathogenesis and immunity is more related, and mainly involved in humoral immunity, Zhu Guangdu et al. reported that vitiligo patients serum IgA, IgG, IgM are higher than the general healthy population, and complement c3 is low, think that humoral immunity is hyperactive, cellular immunity is low is one of the reasons for the above changes. This disease occurs all over the world, the highest incidence in India, about 10,000 people in China, can involve all races, no significant difference between male and female incidence. The most recent research shows that vitiligo will involve eyes and ears in addition to skin, the disease occurs in any age, gender and race, among which young people aged 20 to 30 years old is common, the incidence of the general population is about 0.5% to 4%, in recent years there is an increasing trend. The vitiligo is found in folds and exposed areas, easy to diagnose and difficult to treat, and affects the aesthetics. At present, there is a lack of satisfactory treatment at home and abroad.
In 1988, Koga has used negative pressure suction herpes method to treat vitiligo successfully. In the early days, thin skin slice (0.2-0.3mm) transplantation was manually cut by common skin removal knife, due to the limitation of equipment precision, the skin slice was thick and uneven, and the recovery time was long and not easy to survive after surgery. Electric skin removal knife to cut ultra-thin skin slice, the technical requirements are high, need repeated training to master. If the skin slice is not uniform, it may cause a significant protrusion in the postoperative appearance, but it can generally be adjusted by itself to restore the flatness. If it is still more obvious after six months, it can be treated by grinding or laser grinding. Skin displacement is the main cause of surgical failure in the treatment of vitiligo, there have been reports of using WAB bioadhesive to affix the skin pieces, we use elastic bandage to fix and communicate well with the patient, local braking to reduce the chance of infection and reduce the cost of treatment, also achieved good results.