Coronary heart disease refers to heart disease caused by atherosclerosis of the coronary arteries (coronary arteries) causing narrowing or occlusion of the lumen, leading to ischaemia and hypoxia or necrosis of the heart muscle.
The blood supply to the papillary muscle comes from the terminal branches of the coronary arteries, which are more prone to stenosis and obstruction, so the papillary muscle is sensitive to ischaemia and inadequate coronary perfusion is very likely to cause papillary muscle dysfunction, which controls the opening and closing of the mitral valve, and papillary muscle insufficiency thus leads to mitral valve closure insufficiency, so coronary artery disease can also present with mitral valve closure insufficiency.