Main indications: 1, acne: moderate to severe acne, especially cystic acne, nodular acne and various refractory acne. 2, condyloma acuminata: (especially recurrent condyloma acuminata), flat warts, common warts, etc. 3, skin tumors: basal cell carcinoma, Bowen’s disease, squamous cell carcinoma, paget’s disease (eczema-like cancer), etc. 4, precancerous lesions: solar keratosis, value-added erythema, mucosal white spots, Bowen-like papulosis, etc. 2, photodynamic therapy features: 1, very little trauma; 2, low toxicity; 3, good selectivity 4, can eliminate hidden lesions: can remove latent lesions, subclinical infection, thus reducing the recurrence rate; 5, can protect the appearance and important organ function, retaining the organ shape integrity and normal physiological function; 6, no need to avoid light. The operation procedure of Ira photodynamic therapy: 1, fully explain the treatment method to the patient before treatment and ask the patient to sign the consent form; 2, take clinical photos before treatment 3, drug preparation: use 2ml of gel or water for injection to prepare the drug, modulate 20% 5-aminolevuninic acid (5-ALA) before treatment, the dose is 40mg/cm2, (such as 10 cm2 size lesions, need 400 mg 5-ALA0.4 gALA + 1.6gointment), the whole process must be protected from light; 4, dressing: after the configuration is placed in the refrigerator for a few moments, applied to the affected area; coated with drugs only to reveal the parts to be treated, around the need to protect the treatment towel and aluminum platinum paper cover; 5, sealing package: sealing package time ranging from 1-3 hours, according to the patient’s condition can be selected. 6.Open the red light machine for three minutes, select irradiation 200 J/cm2, fluence 100 mW/cm2 use the light-sensitive rod to test the received energy (adjust the height of the machine so that the lesion receives the required energy), Start (duration: 20-30min) 7.Lighting: seal the package to avoid light 1-3 hours after the light. Pay attention to the wet compress or cold spray after the light; 8. Note 1: Immediately after the treatment, record all kinds of adverse reactions (such as itching, erythema, burning sensation, etc.), and deal with any adverse reactions promptly. 2: Observe any adverse reactions on the next day, and then take clinical photos after the treatment.