Patients have both high-risk and low-risk HPV infections. Low-risk HPV infections usually turn negative within six months to one year. In the case of high-risk HPV infection, the majority of patients will turn negative in less than two years. 10% of patients will have persistent infection that does not turn negative in more than two years. If the infection does not turn negative in more than two years, it may cause precancerous lesions of the cervix. If left untreated at this time, it may lead to cervical cancer. Patients with high-risk HPV infection must be reviewed regularly, once every six months to a year. The review must be combined with a TCT test to see if there are precancerous lesions in the cervix. If precancerous lesions are present, colposcopy will be required.