Thrombosed hemorrhoids can be treated with medication in mild cases, and the clinical situation needs to be based on the condition to decide which medication is effective. The pain can be given ibuprofen and other painkillers, accompanied by constipation can be given lactulose and other diarrhea drugs, accompanied by local infection can be given amoxicillin and other antibacterial drugs, but also can be given to potassium permanganate solution warm water sitz bath treatment. 1. Painkillers: Clinical thrombosed external hemorrhoids will appear severe pain, you can give the relevant painkillers for symptomatic treatment, such as ibuprofen and so on. 2. laxative drugs: because some patients have constipation, during the onset of vascular hemorrhoids, constipation can lead to the aggravation of its symptoms, so you can give the relevant laxative drugs, such as lactulose and other diarrhea drugs. 3. anti-infective drugs: if thrombosed hemorrhoids accompanied by local infections, you can also give relevant antibacterial drugs anti-infective treatment, such as amoxicillin, levofloxacin and so on. 4. potassium permanganate solution: patients can also use potassium permanganate solution for warm water sitz bath, promote local blood circulation, help relieve hemorrhoids caused by hemorrhoid swelling, pain. Conservative treatment is ineffective, can consider giving surgical treatment, please timely hospital consultation, active diagnosis and treatment. The above drugs need to be used under the guidance of a professional physician.