Goserelin shots for adenomyosis have some effect, but the symptoms will remain after stopping the medication. Adenomyosis is the invasion of endometrial glands and mesenchyme into the myometrium, which is related to estrogen level. Goserelin injection is a gonadotropin-releasing hormone agonist, which can reduce or eliminate the pain and reduce the size of the uterus, but the symptoms will return after stopping the medication. Therefore, after 3-6 months of treatment with the drug, it can be supplemented with other treatments for long-term management. Goserelin injection may have some adverse effects such as flushing, excessive sweating, and the possibility of pituitary strokes, manifested by headache, vomiting, changes in vision, and altered mental status, etc. It should not be used if you are allergic to this type of medication. It is recommended to use the drug under the guidance of a doctor, not blindly self-medication to avoid adverse effects.