Bleeding on the 50th day of pregnancy can be caused by pre-eclampsia, ectopic pregnancy, pregnancy combined with vaginal and cervical lesions and external irritation. 1. If the patient has been seen in the hospital in the past and the pregnancy is clearly intrauterine, without abdominal pain or vague abdominal pain, without obvious external factors (external impact on the abdomen, intercourse, etc.), she needs to seek medical attention promptly to clarify the diagnosis. A gynecological examination is needed to consider preterm abortion after excluding vaginal and cervical lesions. At this time, blood HCG and progesterone levels should be rechecked and early pregnancy ultrasound should be repeated. If the ultrasound indicates normal embryonic development, fetus preservation medication can be given, if the ultrasound indicates embryonic abortion, clearance should be performed as soon as possible. 2, the patient has not clearly intrauterine early pregnancy in the past, only home line urine test paper positive, 50 days of pregnancy bleeding does not exclude the possibility of ectopic pregnancy, should promptly hospital consultation to clarify the diagnosis. If there are obvious symptoms of abdominal pain, the patient should immediately consult a nearby hospital for examination, including gynecological examination, blood HCG and vaginal ultrasound. In conclusion, regardless of the cause of vaginal bleeding in the 50th day of pregnancy, it is important to seek medical attention in a timely manner, especially for pregnant women with undetermined intrauterine pregnancy, who need to be alert to bleeding caused by ectopic pregnancy and must seek medical attention as soon as possible for a clear diagnosis.