Bleeding on the 40th day of pregnancy can be caused by pre-eclampsia, ectopic pregnancy, pregnancy combined with vaginal and cervical lesions and external irritation. 1.If intrauterine pregnancy has been confirmed in the hospital in the past, irregular small amount of vaginal bleeding on the 40th day of pregnancy without abdominal pain or vague abdominal pain, except for vaginal and cervical lesions, consider the possibility of pre-eclampsia abortion. If there are no obvious external factors (external impact on the abdomen, intercourse, etc.), consider the possibility of vaginal bleeding due to insufficient hormone levels (HCG or progesterone). In this case, the blood HCG and progesterone levels should be rechecked and the early pregnancy ultrasound should be repeated. If the ultrasound indicates that the embryo is developing normally, but the trend of hormone level growth is unsatisfactory, the pregnant woman should rest in bed and progesterone drugs can be used to keep the fetus; if the ultrasound indicates that the embryo has stopped developing, it is necessary to perform the uterus removal as soon as possible. 3.If early intrauterine pregnancy has not been clearly identified in the past, only positive urine test paper at home, bleeding for 40 days of pregnancy does not exclude the possibility of ectopic pregnancy, timely hospital consultation should be made to clarify the diagnosis, if accompanied by obvious abdominal pain symptoms, more immediately to a nearby hospital. If the result shows ectopic pregnancy, most of them need to be treated by surgery. In conclusion, regardless of the cause of vaginal bleeding around 40 days of pregnancy, it is necessary to seek medical attention in time, especially for pregnant women with undetermined intrauterine pregnancy, who need to be alert to vaginal bleeding caused by ectopic pregnancy, which may endanger the life of the pregnant woman and must seek medical attention as soon as possible for a clear diagnosis.