1. My child’s glutathione, glutamic acid, total bilirubin and direct bilirubin have always been within the normal range, but I found that alkaline phosphatase and lactate dehydrogenase are higher than one at a time, and I don’t know what these two high levels mean. What should I do? Is it medication or diet? High alkaline phosphatase is related to calcium and phosphorus metabolism, so pay attention to long-term calcium supplementation and vitamin D treatment; in children, alkaline phosphatase activity can be 1 to 2 times higher than normal during the physiological bone development period, and it can also be elevated in adolescents in the growth period. However, alkaline phosphatase needs to be alerted to cholestatic liver injury if it exceeds 2 times the normal value. If lactate dehydrogenase is persistently high and significantly exceeds the normal value, it needs to be alerted because its index will be high when the tumor is active, so pay attention to regular bone marrow examination. 2.If I don’t eat 6MP according to the basic amount during the oral maintenance period, is it also possible to control the white blood cells between 2-3 even if I don’t eat enough? Is it medically important to look at the white blood cells, or is it important to eat enough medicine? Generally speaking, since there are significant individual differences in each child’s response to 6MP, we adjust the dosage mainly based on the white blood cell count, which means trying to control the white blood cells between 2-3. This achieves the purpose of treating leukemia without making the leukocyte suppression too low and prone to organismal infection. 3, oral just started, it is difficult to control many small details of life did not do well, resulting in children because of fever and itchy rash stopped 2 times 6MP, oral period is always stopping the drug is not very good ah? The most important thing is to learn more about the experience and reduce the infection, of course, it is better to try not to interrupt the medication. You are already a very attentive parent, cheers! 4.Do I still need to give my child oral sulfonamide regularly during the maintenance treatment? Cotrimoxazole (cotrimoxazole) – we often call it “sulfa” for short. During maintenance chemotherapy, the child’s immune system is also very weak and susceptible to Pneumocystis carinii pneumonia, which can be very serious and even life-threatening! Therefore, during leukemia maintenance, we also recommend the need to take oral sulfonamide regularly, usually at least 2 rounds (one round of three days) per month. 5.Can the child move around normally during maintenance treatment? During the maintenance treatment period, you can choose an open outdoor activity place for walking, jogging, playing badminton, etc. You can gradually increase the amount of activity according to the child’s physical strength, so as not to feel fatigue.