If the Hepatitis B half-pair indicates a minor triple positive, this is not indicative of the exact time of infection. The time of infection needs to be determined by a combination of the patient’s medical history and other circumstances. Many patients with hepatitis B minor triple positive are caused by mother-to-child transmission. If the mother also carries the hepatitis B virus, then this is the time of infection at birth. If there is no family history of hepatitis B, this situation should be traced to the past whether there are blood transfusions, drug use, blood sales or beauty, eyebrow tattooing, etc., because these behaviors are likely to be infected with the hepatitis B virus, according to the time of occurrence of these behaviors, in the roughly presumed infection of the hepatitis B virus at the time. Clinically, there is no way to determine the time of infection of hepatitis B. Hepatitis B minor triple positive should be regularly tested for relevant indicators, pay attention to rest, and develop good living habits.