Patients with mouth ulcers who want quick pain relief can try applying watermelon cream, lidocaine gel, etc. in appropriate amounts to the ulcer site, which usually has some effect. However, since the degree of mouth ulcers varies from patient to patient, there is no guarantee that they can all achieve quick pain relief. If the ulcer symptoms are more serious and cannot be relieved for a long time, it is recommended that patients seek medical attention and take appropriate treatment under the guidance of a doctor. A. Topical drugs: 1. pain medication: such as benzocaine gel, bendamycin spray, etc., can quickly relieve pain, but it is not recommended for long-term use to avoid the formation of drug dependence; 2. anti-inflammatory drugs: such as chlorhexidine gargle, diquat chloride tablets, etc., can reduce inflammation and relieve symptoms; 3. drugs to promote healing: such as oral ulcer dispersion, watermelon cream and recombinant human epidermal growth factor gel, etc., can promote the ulcer surface The healing of the ulcer surface. Internal drugs: 1. vitamins: such as vitamin B1, vitamin B5, vitamin C, etc., can maintain the normal metabolism of epithelial tissues and promote ulcer healing; 2. antibiotics: such as benzocillin, cefixime, etc., can help promote healing and prevent infection; 3. immune preparations: such as thalidomide, transfer factor, etc., can improve the immunity of the patient’s organism and promote ulcer healing. Physical therapy: such as laser, microwave, etc., can reduce ulcer exudation and have certain effect on pain relief and promote ulcer surface healing. In addition, patients with mouth ulcers need to pay attention to keeping the mouth and teeth clean and hygienic, drink more water, and eat more fresh vegetables and fruits rich in vitamins, such as tomatoes, oranges, carrots and so on. Avoid spicy and irritating foods. Ensure sufficient sleep to facilitate the recovery of the disease.