Long blister that is clinical herpes, a blister under the tongue is considered to be the recent intake of too much spicy, stimulating, cold, greasy diet, such as alcohol, spicy hot pot, seafood, fried food caused by inflammation of the sublingual gland, it is recommended that the patient’s diet to light, easy to digest rice soup, egg noodles, lotus root powder, as well as fresh fruits and vegetables, generally able to heal themselves. In addition, the following disease factors may also cause patients to grow blisters under the tongue: 1, sublingual gland cyst: is a type of mucus gland cyst (salivary gland mucus cyst), the prevalence of adolescents. It is mainly due to poor oral hygiene, intake of hard textured food, such as potato chips, fried chicken, fried cake, etc., as well as fish spines, bones and other food residues damage the salivary gland ducts, causing inflammation. At the same time, oral factors such as bending of the duct system and concentration of secretions can also induce cysts. Cysts are generally translucent blisters, easily ruptured to secrete egg-white like or slightly yellow sticky liquid; 2, oral herpes simplex: caused by herpes simplex virus infection, manifested as herpes on the oral mucosa and perioral skin, with herpetic stomatitis being the most common. The development of herpetic stomatitis to the blistering stage can occur in any part of the oral mucosa, including small blisters under the tongue, the wall is thin and transparent, self-rupture to form a superficial ulcer; 3, vascular malformations: vascular malformations are commonly found in the tongue, the floor of the mouth and other parts, if the lesion site is deep, it does not show obvious mucosal changes, while superficial lesions can be manifested as blue or purple mucosal changes, soft to the touch, may make patients mistaken for the tongue under the 4, other: for example, submandibular duct stones in the lower part of the tongue, causing the patient’s salivary gland secretion discharge obstruction, retention cysts, can also be manifested as blisters under the tongue, will affect the patient usually eat. For these conditions, patients need to improve their diet and supplement with nutrients and vitamins. At the same time, patients need to take medication under the guidance of doctors. Common antibacterial drugs include cefuroxime, cefixime, metronidazole, penicillin, etc., and antiviral drugs such as acyclovir and ribavirin. In addition, sublingual gland excision is the radical treatment for sublingual cysts. Therefore, if necessary, patients are still advised to visit a hospital in time to choose the best treatment plan according to their condition and prevent the disease from happening.