(Disclaimer: This article is for scientific use only, and the information in the following content has been processed to protect patient privacy) Abstract: This 37-year-old male patient with a history of 2 previous acute pancreatitis, the second occurrence of acute necrotizing pancreatitis, was discharged after treatment at an outside hospital and improved, and after regular review after discharge, was found to have pancreatic pseudocyst formation with abdominal pain and discomfort, so he was referred to our hospital and perfected After completing the relevant examination, the patient was given surgical treatment and medication, and was discharged from the hospital with significant improvement of abdominal discomfort. Basic information】Male, 37 years old 【Disease type】Pancreatic pseudocyst 【Visiting hospital】The First Affiliated Hospital of Kunming Medical University 【Visiting time】May 2022 【Treatment plan】Surgical treatment (jejunum Roux-en-Y anastomosis) + intravenous infusion (ceftriaxone sodium for injection, esomeprazole sodium for injection, glucose sodium chloride injection) 【Treatment cycle】Inpatient treatment for 18 days 【Treatment effect】Abdominal discomfort improved significantly. One day in May 2022, a patient with an abdominal mass arrived at the outpatient clinic. The patient reported that after being discharged from the hospital 8 months ago with acute necrotizing pancreatitis, he came to our hospital after regular outpatient review of the enhanced CT showed pseudocyst formation in the pancreatic area. The patient had no symptoms of nausea and vomiting, no yellow staining of the skin and sclera, no acid reflux and belching during the course of the disease, and the patient was given a follow-up examination, which showed progressive enlargement of the pancreatic pseudocyst, and the patient had been feeling pain and discomfort in the lumbar abdomen for the past half month. In addition, the patient had a previous history of pancreatitis. After brief communication with the patient, he was suggested to be hospitalized, and the patient understood and agreed. II. Treatment After admission, the patient completed relevant examinations and was given routine blood, urine, biochemical, infectious disease and coagulation examinations, which were generally normal. On examination, the patient’s abdomen was flat, and there was no pressure pain or rebound pain in the abdomen; abdominal masses could be palpated on the right and left side of the abdomen, with no fluctuating sensation and hard texture, and the right abdominal mass was larger. The diagnosis of pseudocyst was clear, and the estimated time of onset was more than 6 weeks. The pseudocyst was large and it was appropriate to perform surgery. After communicating with the patient and his family about the risks associated with the surgery, the patient agreed to the surgery and signed the informed consent form. After that, we arranged the Roux-en-Y anastomosis of the jejunum, left a drainage tube to drain the patient, and sutured the surgical incision. The procedure went smoothly and the patient returned to the ward safely. Postoperatively, the patient was given anti-inflammatory ceftriaxone sodium for injection, along with esomeprazole sodium for injection to suppress gastric acid and sodium chloride glucose injection for rehydration. (Diagnosis) III. Treatment effect Postoperatively, the patient was told to lie flat for 12 hours and to abstain from food and water. The patient felt slight pain in the surgical incision 2 days after surgery, and no blood leakage or infection was observed. After about 18 days of comprehensive hospitalization, the patient’s mental status was acceptable, sleep was acceptable, abdomen was flat, pain and discomfort in the lumbar abdomen were significantly relieved, while there was no abdominal pressure pain or rebound pain, and bowel sounds were normal. The patient and his family requested to be discharged from the hospital, and informed the patient of the precautions given after discharge from the hospital. IV. Precautions The old problem that has been bothering the patient for many years was solved, and we are sincerely happy for it. The patient’s treatment time in the hospital is relatively short, and more time needs to recuperate at home on his own. Therefore, the patient is advised to pay attention to whether the incisional auxiliary material has any blood and fluid leakage and pain during recuperation at home, and to inform the medical staff by phone in time to confirm whether a follow-up consultation is needed if the above situation occurs. It is advisable to have a light diet, avoid eating greasy and spicy food, and pay attention to eating less and more meals; at the same time, develop good habits of work and rest, go to bed early and wake up early to help control and stabilize the disease. V. Personal insight The pancreatic pseudocyst in this patient is mostly considered to be secondary to recurrent acute necrotizing pancreatitis, because the wall of the cyst is not composed of a specific cell wall unique to a real cyst, so it is called a pseudocyst. Acute pancreatitis is also a common cause of pancreatic pseudocysts clinically, and the pain and discomfort in the lumbar abdomen of the patient in this article is also a common symptom presentation, and surgery is recommended due to its long duration and relative severity. Therefore, patients with previous pancreatitis should also be reminded that they should be reviewed regularly to prevent the formation of pancreatic pseudocysts, and they must go to the hospital promptly when they have any uncomfortable symptoms for early intervention and early treatment.