The proverbial eyelid jumping, which I believe most people have experienced, is mostly related to poor rest and nervousness and can go away automatically in the short term. If it persists and even develops into a twitching at the corners of the mouth, then it is likely to be a “facial spasm”. This is a disease that cannot be cured by itself. The typical manifestation is a twitching of half of the face from the corner of the eye to the corner of the mouth, which is obvious after stress, excitement or exertion. Severe cases even lead to persistent muscle spasms, resulting in difficulty in opening the eyes, or changes in facial appearance. The muscle twitches are painless and the patient is not abnormal during the interictal period. The course of disease development is generally long, often over a year or even several years. At present, the Internet is full of all kinds of false information propagating facial muscle spasm, which is easy to mislead the public and needs to be popularized by professional doctors. Facial spasm is a functional neurological disorder, and the muscle twitching itself is not life-threatening. However, the psychological impact of the disease on patients is enormous. For example, many patients involuntarily twitch when meeting strangers, thus creating low self-esteem, depression and anxiety, which seriously affects normal work life. The diagnosis of typical facial muscle spasm is not difficult and can be completely cured by proper treatment, but it needs to be differentiated from muscle twitching and habitual twitching behind facial palsy. It is now believed that the onset is caused by the compression of blood vessels at the root of the facial nerve in the brain, and the use of surgical procedures to move the blood vessels away from the root of the facial nerve is the most fundamental means of treatment for facial spasm, called facial nerve root microvascular decompression.