Infections in these areas can directly damage the spermatogenic tissues of the testes and cause obstruction of the ducts, or they can be caused by bacterial toxins in the seminal plasma that can affect sperm activity. How do you know that infertility is caused by a reproductive tract infection? The diagnosis is made when a prostate biopsy or bacterial culture indicates an infection, or when the sperm count and motility of semen with a negative bacterial culture are lower than those with a negative culture. Therefore, some scholars believe that leukocytosis is a basis for infection. So they treat it with various antibacterial and anti-inflammatory drugs. Is this view right? It should be said that it is not entirely correct. Because in human semen, in addition to normal semen, there are some immature sperm cells at different stages of development, these cells are also round, and larger, direct observation under the microscope or stained with a general smear, it is difficult to distinguish from leukocytes, if these sperm cells are also treated as leukocytes, and put on the “hat” of reproductive tract infection If these sperm cells are also treated as leukocytes, and given the “hat” of reproductive tract infection, obviously is one-sided. Therefore, special staining methods must be used to first determine if there are really more white blood cells. Also even if there are more leukocytes in the semen, indicators such as the number and motility of sperm and the positive rate of semen culture are not closely related to it. Therefore, the diagnosis of infertility caused by reproductive tract infections requires a comprehensive analysis based on all aspects of the examination data, rather than jumping to conclusions based solely on the presence of a few white blood cells in the semen, resulting in the blind use of drugs without the desired therapeutic effect.