Multi-resistant bacteria refers to bacteria resistant to three or more types of clinically effective antibiotics (at least one antibiotic in each type) at the same time, usually caused by antibiotic abuse, bacterial mutation and other reasons, the infection is mainly prevented by avoiding the abuse of antibiotics, avoid cross-infection and other methods, the infection is mainly controlled and treated through strict compliance with medical advice medication. A, prevention methods 1, avoid the abuse of antibiotics: First of all, we need to pay attention to the application of antibiotics should follow medical advice, only when there is a clear infection, antibiotics can be used, not private application or over application, so as to avoid the abuse of multi-drug-resistant bacteria, and then multi-drug-resistant bacterial infection; 2, pay attention to cleaning, disinfection: daily attention to diligent hand washing, diligent ventilation, indoor environment and daily use of items regularly appropriate 3, avoid cross-infection: try to avoid sharing a confined space with the infected person, if there is a need for contact, pay attention to wearing a mask, try to maintain a certain distance, pay attention to hand hygiene. And we need to pay attention to avoid sharing dishes, chopsticks and other daily necessities with infected people to avoid cross-infection, which can help reduce the chance of multi-drug resistant bacteria infection. Second, control measures 1, follow medical advice medication: for patients who have been infected with multi-drug resistant bacteria, need to select a reasonable and effective antibiotics according to the results of drug sensitivity tests for antimicrobial therapy; 2, pay attention to diet: these patients need to pay attention to diet, to ensure adequate nutritional intake, to provide patients with sufficient energy, help improve physical fitness, and facilitate recovery.