The discontinuation time of Rosuvastatin is related to the lipid profile and disease status. Simple lipid-lowering therapy can be discontinued when the lipid profile is reached, while when used for atherosclerotic cardiovascular disease, it is usually taken for life. Rosuvastatin is a lipid-lowering drug with the main purpose of lowering LDL cholesterol. It is mainly used for the treatment of hypercholesterolemia, atherosclerosis combined with hyperlipidemia and coronary heart disease. However, some side effects can occur with long-term use, such as diabetes, neurological abnormalities, gastrointestinal abnormalities, skeletal muscle, joint and bone abnormalities, weakness, subcutaneous and subcutaneous tissue abnormalities, allergic reactions, hematuria, and elevated transaminases. Therefore, the drug can be discontinued when there are serious side effects or when the blood lipids drop to normal levels after taking lipid-lowering drugs, and when the blood lipid levels can all be controlled through diet and exercise therapy. Patients who use it for the treatment of coronary heart disease and cerebral infarction usually need to take it for a long time. Rosuvastatin is usually recommended to be taken after dinner or at bedtime. Patients should take and discontinue the drug as prescribed by their doctors and should not make any decisions.