Metatarsal fracture two months or swelling is related to the inflammatory response at the fracture end and the blood circulation around the fracture end, oral anti-inflammatory drugs or blood-activating drugs can relieve the swelling. 1. Inflammatory reaction: Inflammatory edema at the fracture end of the metatarsal bone due to aseptic inflammation. Therefore, oral non-steroidal anti-inflammatory drugs such as acetaminophen, ibuprofen, or celecoxib can improve the inflammatory reaction, and then relieve the local swelling. 2. Poor blood circulation: Metatarsal fracture will damage the blood vessels around the fracture causing blood circulation disorder, so the fracture can be taken orally to activate blood circulation medication such as Mazolins and other drugs. In addition, two months after metatarsal fracture, the broken end of the fracture is in the period of primitive bone scab formation, the broken end of the fracture is still unstable, the movement of the broken end of the fracture will stimulate the oedema and oozing of the surrounding tissues, in the fracture end of the primitive bone scab formation and stabilization of the result, the oedema can gradually disappear. Medications to treat swelling caused by metatarsal fractures need to be taken under the guidance of a doctor.