With the progressive understanding of severe acute pancreatitis, its treatment rate has increased from about 30% in the 1970s to 85% at present. However, the cost of medical treatment is a well-known fact. Therefore, prevention and early treatment are important measures to reduce medical costs. If there are microscopic stones in the gallbladder and sediment-like stones in the intrahepatic bile ducts, surgical treatment should be performed as soon as possible, especially in patients who have had an episode of mild pancreatitis, the gallbladder should be removed in a timely manner. Some people may think that pancreatitis will not occur after the removal of the gallbladder, but in fact, there are still a few patients who can have pancreatitis again. Why is that? The reason is that the root cause of gallbladder stones is the abnormal secretion of bile from the liver, and the removal of the gallbladder only reduces the chance of pancreatitis, but does not completely eliminate it. So how can we prevent the recurrence of pancreatitis after gallbladder removal? Generally speaking, we need to take cholestatic drugs such as ursodeoxycholic acid and goose deoxycholic acid regularly. The second common cause is hyperlipidemia, triglycerides in the blood >5.65mmol/L, which are at a high level for a long time, and even 63mmol/L in some patients, so as long as the triglycerides in the blood exceed the above value, it is necessary to reduce the blood lipids to the normal range through diet and oral lipid-lowering drugs, and regularly recheck the blood triglycerides. In general, elevated cholesterol does not cause severe pancreatitis. The long-term alcohol consumption is another cause of severe pancreatitis, combined with binge drinking on top of long-term heavy alcohol consumption can cause severe acute pancreatitis, long-term alcohol consumption is mainly for people who are more social, which is the most dangerous group of people. Long-term heavy drinking can lead to chronic damage to the pancreas, and its onset is based on the acute onset of chronic lesions in the pancreas, and this causes severe pancreatitis is more difficult to save. The above are the 3 common causes, less common is the onset of severe pancreatitis in women during pregnancy, mainly related to hyperlipidemia and estrogen levels, in terms of prevention, blood triglycerides can be reviewed regularly. Other more rare cause is hypercalcemia, which is often secondary to elevated blood calcium due to hyperparathyroidism, and if there is a parathyroid adenoma and elevated blood calcium, the adenoma should be surgically removed as soon as possible. When severe acute pancreatic has occurred, it should be treated in an experienced hospital as soon as possible, the golden time for this disease is 72 hours from the beginning of the stomach pain, once this period is exceeded, some patients can develop into a very serious state, and the medical costs are very high. 72 hours to receive regular treatment effect is half the effort, but after 72 hours, it may be half the effort, so we must The earlier the patient receives formal treatment, the better the prognosis.