After the movie “Don’t Disturb Me II” was released, the number of patients coming to our aesthetic clinic for mole removal increased, and many of them came to our clinic because they were afraid of malignant changes in their moles after watching the movie. Pigmented nevus, also referred to as nevus, nevus or nevus, is a benign tumor of the skin most commonly composed of normal pigmented nevus cells and occasionally seen on the surface of mucous membranes. There are various types of clinical manifestations. Most of them are dark brown or black in color, and there are also colorless nevi without color. They are found on almost everyone. Moles on the face are an eyesore and many people have them removed or cut off. But few people care about the moles that grow on hidden parts of the body. It is because they do not care that moles become melanoma in the movie. There are three types of pigmented moles according to pathology: ① Intradermal moles: exist in the dermis. The surface is smooth and the boundary is clear. They are larger than 1 mm, grow in patches, and are flat or slightly elevated. The color is dark and uniform, light brown, dark brown or inky black. Generally no carcinogenesis occurs. ②Junctional nevus: located at the junction of epidermis and dermis. They are mostly found on the palms of hands, soles of feet, lips of mouth and external genital area. The surface is flat or slightly high, and the size is between 1-2 mm, light brown, brown-black or blue-black. There is a possibility of cancer, which can occur as melanoma. ③Mixed nevus: It is a mixture of the above two kinds, generally like intradermal nevus, and can be cancerous because it has components of junctional nevus. All nevi can be found in all parts of the skin, with the face, neck and back of the chest being the most common sites. At present, it is believed that repeated stimulation such as rubbing, needle picking, incomplete excision, light, electrocautery, erosion with drugs and their own endocrine disorders may be the triggering factors for the malignant transformation of junctional nevus or mixed nevus into melanoma. Once a pigmented nevus becomes malignant, its malignant degree is extremely high, and the metastasis rate is also the fastest, and the treatment effect is not ideal. Commonly used methods of mole removal.
The way of mole removal usually depends on the type, size and location of the mole. Generally speaking, it is more difficult to grasp the depth of ordinary CO2 laser, freezing, ultra-high frequency electricity, chemical peeling, etc., and it is easy to leave scar or the treatment is not complete, so try to remove it surgically. Especially if it is more than 3 mm, it has to be removed. Since malignant changes usually occur after the age of 30, the time to remove them can wait for adulthood. Congenital giant nevus should be removed as early as possible after birth because the malignancy rate is higher and half of the malignant changes occur before the age of 5. In addition to aesthetic factors, the following types of moles should be removed in order to avoid becoming malignant melanoma: ①Moles that grow on the extremities of special parts (hands and feet), especially under the finger (toe) nails. ②Moles of mucous membrane. ③Moles that can be stimulated by long-term friction, such as moles that grow at the place where bras are worn and at the waist. ④Moles with atypical changes. ⑤Sudden and rapid change of a single mole. (6) Congenital giant moles. Be alert to ten kinds of pigmented moles that are prone to cancer: ①Pigmented moles usually appear from birth to 30 years old, and new pigmented moles appearing after 30 years old should be suspected. ②Pigmented nevi with repeated infections. ③When the pigmented nevus has a tendency to bleed. ④Sudden appearance of persistent itching in pigmented nevi. ⑤If there is inflammatory redness around the pigmented nevus or satellite nevus appears around it. (6) Sudden loss of the original hair on the pigmented nevus. ⑦The surface of the pigmented nevus is moist or there is crust formation. ⑧The pigmented nevus is stimulated by friction or trauma repeatedly for a long time, and there is a potential cancer factor. (⑨) When hard nodes or ulcers or bleeding appear in the center of pigmented nevus.
⑩The darkening of pigmented nevus is not an absolute indication of malignant change, because all pigmented nevi can become dark when they are sexually mature and pregnant. However, if any single mole becomes darker than other moles in a short period of time or becomes unevenly black, or if it increases rapidly, it is an early sign of cancer. When some of the above symptoms appear, you should go to the Burn Plastic and Reconstructive Surgery Department of the hospital for examination and consultation in time for early detection and reasonable treatment. The specialist will divide the patient’s nevus into two, and one part will be biopsied to confirm whether it is malignant melanoma; if it is diagnosed as malignant melanoma, the other half can be used to do specific immunotherapy for the patient, which can greatly improve the chance of cure.