Lip spots may be caused by melanosis, pigmented nevus, melanoma, etc., which can generally be removed by freezing, laser and surgical treatment. 1. melanosis: melanocytes produce too much melanin, which is excessively deposited in the epidermal keratinocytes of lips, resulting in lip spots, which can be treated by laser to achieve the purpose of removing pigmentation. 2. pigmented nevus: lip spots may be pigmented nevus occurring at the corners of the mouth, often as spots and patches. Most pigmented nevi do not require treatment, and when patients have aesthetic requirements, they can be removed through surgery or physical therapy; 3, melanoma: the appearance of new pigmented spots on the skin with unusual growth may be melanoma, which may have symptoms such as itching and bleeding. It is usually treated by surgery and post-operative adjuvant radiotherapy and chemotherapy. Usually pay attention to avoid sun exposure, wash face with warm water and avoid eating too hot. If the spot grows rapidly recently with symptoms such as itching, breaking and bleeding, it is recommended to seek medical treatment in time.