Cough does not necessarily decrease after the first chemotherapy treatment for small cell lung cancer; chemotherapy is not a treatment for cough. If the cough is caused by the tumor compressing the trachea and the chemotherapy treatment is effective, the patient’s cough may be reduced. Chemotherapeutic drugs do not have the effect of relieving cough and resolving phlegm, if the cough is caused by non-tumor factors, relevant symptomatic treatment should be carried out to alleviate the symptoms, if the cough is caused by the tumor pressing the trachea and the tumor is effective in chemotherapy, then it is possible to reduce the cough after the first chemotherapy. Chemotherapy is an effective measure for cancer treatment, but it may also produce adverse reactions. Chemotherapy for small cell lung cancer patients can produce many adverse reactions, such as vomiting, nausea, loss of appetite, weakness, hair loss, drop in blood cells and other adverse reactions. If the side effects of chemotherapy are more serious, you should not force chemotherapy. Patients with small cell lung cancer cough need to actively consult the doctor, understand the condition according to the examination results, and use medication according to the standardized treatment under the guidance of physicians.