Panic chest tightness breath holding chest pressure may be coronary atherosclerotic heart disease, vegetative nerve disorders, myocarditis and other diseases lead. 1. Coronary artery atherosclerotic heart disease: coronary artery atherosclerotic heart disease is due to cholesterol latter other deposits composed of plaque in the arterial wall accumulation, patients will appear angina pectoris, chest pressure, shortness of breath, palpitations, panic and other symptoms. As a result, patients will experience panic chest tightness and breath holding chest pressure. 2. Phytoneurotic disorder: phytoneurotic disorder is caused by psychosocial stress and other factors, the patient’s main symptoms are cardiothoracic chest tightness, breathlessness, panic, near-death sensation and so on, so the patient will have panic, chest tightness, breathlessness and chest pressure symptoms. 3. Myocarditis: Myocarditis is caused by infection, autoimmune factors and other factors. Patients will have palpitations, chest tightness, shortness of breath, chest pain and other manifestations, so patients will have panic, chest tightness, breathlessness and chest pressure. When patients experience symptoms of panic, chest tightness, breathlessness and pressure in the chest, it is recommended that they seek medical attention in a timely manner to identify the cause of the disease and treat it under the guidance of a doctor.