”Flood” is often used to describe a dangerous, critical and frightening situation. In the minds of many people, AIDS is a beast. Fear of AIDS, refusal to have contact with AIDS patients, and refusal of necessary invasive treatment due to fear of being infected by HIV are all common manifestations of “AIDS-phobia”, but these are only normal reactions of people, not yet to the point of “disease”. However, these are normal reactions and do not rise to the level of a “disorder. This article will describe another type of “Islamophobia” that has reached a pathological state and even requires medical intervention. As an infectious disease physician, I am also afraid of AIDS, but my fear has a different cause. Not long ago, I saw a young man in his twenties working in Shanghai who claimed to have an “unexplained fever”. He had a normal temperature and no signs or symptoms at the time of the visit, but he was clearly anxious in his speech and had no abnormal results from any of the tests he could provide. When I diagnosed him with a simple viral infection, the young man suddenly interjected, “Dr. Miao, do I have AIDS? How long can I live?” With my experience, I knew the story was about to begin. So the young man recounted the story of a misadventure six months ago, and his subsequent experience of persistently consulting information, constantly running to hospitals, and stubbornly requesting various laboratory tests. He finished his story in 30 minutes, while I used my professional knowledge and experience, and also spent half an hour on detailed explanation and enlightenment, which seemed to make the other party understand that he was not HIV-infected. A week later, the young man registered for my special needs clinic again, complaining that he was “a little nervous about his last visit and had a few questions to ask”, so we talked for another three quarters of an hour about the possibility of being HIV-negative for AIDS. I breathed a sigh of relief after sending him away for the second time. However, a week later, his name came up again on my patient appointment list and this time, I was devastated! I was terrified! Another long conversation, another heartfelt explanation. But in the end, I had to “push” him to the AIDS specialist at the Shanghai Public Health Clinical Center. Readers, this is a long and tedious story, but I believe that you already understand that the patient I saw was pathological, with a serious psychological disorder, suffering from a typical “Islamophobia”. Patients who suffer from “Islamophobia” usually have had high-risk sexual behavior, most often in men, often after having even one sexual relationship with an undercover prostitute. Patients at first have self-blame and remorse for their behavior, and slowly, contradictions, guilt and shame deepen and are difficult to eliminate; they also learn a lot of AIDS-related knowledge through various means afterwards, and consciously or unconsciously put certain signs and symptoms of AIDS in their own “seat”, and therefore repeatedly After repeatedly testing for HIV antibodies and viral genes, they are unwilling to believe the test results. This creates a vicious cycle that gradually leads to anxiety, irritability and paranoia, and a very small number of people claim to be suffering from the so-called “negative AIDS”, i.e., virus-negative AIDS, which eventually develops into a completely uncontrollable obsessive-compulsive disorder. This is a real mistake! This phenomenon or this group of people has become a social problem, and even epidemiologists are not afraid to say what is right and what is wrong publicly. The early stages of HIV infection can be asymptomatic, and it can take up to 10 years for impaired immune function to accumulate before symptomatic AIDS develops. The most basic evidence to confirm HIV/AIDS infection is the presence of HIV replication in the body, based on positive HIV antibodies and/or positive HIV nucleic acid, or more precisely, positive antibodies or nucleic acid to confirm HIV infection. It is important to explain the concept of “window period”, which refers to the “gap” between the time of HIV infection and the appearance of antibodies. The World Health Organization has determined with certainty that the window period after HIV infection is 14 to 21 days, with a very small number of infected individuals having a window period of 3 to 6 months. Many people with Islamophobia are tormented by this window period after they “commit”, and their long-term worry and anxiety eventually develop into a serious psychological disorder that is difficult to reverse. While we sympathize with these very few AIDS-phobic patients, we would like to give some suggestions: (1) cleanliness is the first thing to prevent various sexually transmitted diseases, including AIDS, which may ruin your life and family, and even become a social instability. (3) the need to master some scientific knowledge, the purpose is to prevent disease and receive the correct diagnosis and treatment, but do not get too deep, non-medical personnel can not be comprehensive and accurate knowledge of HIV infection, otherwise it will be counterproductive; (4) HIV infection can not be cured, but it is a chronic disease (5) HIV is transmitted vertically through injections, sexual intercourse and mother-to-child transmission, but fundamentally through blood transmission, so there is no risk of daily contact with HIV-infected people; (6) medical personnel, intravenous drug addicts, “sex workers”, sexual promiscuity and homosexuals are (6) Medical personnel, intravenous drug users, “sex workers”, sexually promiscuous and homosexuals are high-risk groups, but the majority of infected people are those who inject drugs intravenously, have multiple sexual partners and are gay men; (7) The whole society should care about people with HIV/AIDS, and there is no reason to discriminate against them; (8) The number of young students infected with HIV is increasing rapidly, and their cognitive and psychological ability is weak, so they need more guidance and education. There is no vaccine to prevent HIV infection yet, scientists have been working hard on it, and it will not be long before a vaccine is available; meanwhile, a cure for AIDS is not far away. The fear of HIV and the fear of AIDS patients will be gradually eliminated with medical development.