Trigeminal neuralgia is a disease of recurrent paroxysmal severe pain in the distribution area of the trigeminal nerve, the cause of which is unknown and may be secondary to other diseases. It is a common painful disease that seriously affects the quality of life of the majority of patients, especially the elderly. The diagnosis of the disease is easy, but it is difficult to get rid of the root cause. The traditional treatment is to use painkillers for symptomatic treatment, but must be taken for a long time, with the prolongation of the course of the disease must be constantly increase the dosage of drugs, the effect is getting worse and worse. Patients are prone to anemia, liver and kidney function damage and toxic side effects in the digestive system. Trigeminal nerve semilunar section radiofrequency thermocoagulation is a minimally invasive interventional surgical treatment, without incision, the patient can not feel the pain, first of all, the use of CT or “C” shaped arm and other image guidance and localization, minimally invasive puncture in the patient’s corner of the outside of the mouth, so that catheter needles to reach the patient’s patent foramen ovale, the application of intermittent pulsed current sensory stimulation and motor stimulation to test stimulation area and the patient’s pain episodes area match or not, so as to make the treatment more delicate and safer. Because the unmyelinated fine fibers that conduct pain degenerate at 70°-75°C, while the myelinated coarse fibers that conduct touch can tolerate higher temperatures, temperature-controlled thermocoagulation is to control the destruction temperature at 75°C, so that it can take advantage of the differences in the temperature tolerance of different nerve fibers to selectively destroy fine fibers in the semilunar ganglion that conduct pain in the face and to preserve coarse fibers in the semilunar ganglion that conduct touch, which have a greater resistance to heat. The thicker fibers that conduct the sense of touch are preserved, which are more resistant to heat. The goal of immediate pain relief and preservation of facial sensation is achieved. “Semilunar ganglion radiofrequency thermo-coagulation” is suitable for: primary trigeminal neuralgia, the effect of medication is not ideal; Carbamazepine and other painkillers have obvious adverse drug reactions; old and frail can not tolerate craniotomy treatment of trigeminal neuralgia patients; do not want to accept open trigeminal nerve vascular decompression; open trigeminal nerve vascular decompression recurrence of the patient; controlled radiofrequency thermo-coagulation treatment recurrence of the patient, you can coagulation treatment again; those who have unsatisfactory effect of gamma knife treatment and the pain is not eliminated or reduced; those who have trigeminal neuralgia due to tumor and the pain is not improved by gamma knife or surgical treatment.