Ovaries are the unique reproductive organs of women, and the eggs discharged from the ovaries are the source of conception of life. However, in reality, there may be one reason or another that causes irreversible damage to the ovarian function, or even make the ovaries lose ovulation and endocrine function, resulting in female infertility. Therefore, some patients will choose to freeze and save part of the ovarian tissue, and when necessary and physically permissible, they can undergo autologous transplantation, which can realize the restoration of female reproductive ability and ovarian endocrine function, in order to achieve the purpose of fertility. The transplantation of autologous tissue avoids ethical issues. What are the adaptive groups of ovarian tissue freezing? 1.Young women who need postoperative radiotherapy/chemotherapy for malignant tumors, such as cervical cancer, endometrial cancer, and bone marrow transplantation, because radiotherapy or chemotherapy has damaging effect on ovarian tissues, preserving ovarian tissues before the treatment will preserve the hope of fertility. 2. For those with high risk of premature ovarian failure, part of the ovarian tissue can be frozen when they are young, and then the saved ovarian tissue can be transplanted after the function of the ovarian tissue decreases, in order to realize the restoration of the endocrine function of the ovary. 3.Patients with severe damage to ovarian tissue, such as patients with severe endometriosis, which can damage the patient’s ovarian function, can also have their ovarian tissue preserved first. 4. In the surgical treatment of benign diseases, operations such as electrocoagulation will damage normal ovarian tissues and can cause degenerative lesions of the ovaries, so some tissues are taken for preservation before ovarian surgery to preserve normal ovaries, which may be applied to hormone replacement therapy for menopausal women in the future.