Clinically used antipyretics for children include acetaminophen, ibuprofen, nimesulide, and herbal antipyretics. When the body temperature is <38.5℃, it is not recommended to use antipyretic drugs, but to take physical cooling methods first, such as giving the child more water, warm water baths, and applying antipyretic patches. The body temperature > 38.5 ℃, and then oral antipyretic drugs. 1, acetaminophen: the most commonly used clinically is the acetaminophen class of antipyretic drugs, acetaminophen class of antipyretic drugs for infants and children over 2 months of age, its main preparations include oral liquid and suppositories. If the child has no gastrointestinal reaction, the oral liquid formulation is usually the clinical choice. If the child is accompanied by obvious nausea, vomiting or difficulty taking medication, in this case you can choose to use acetaminophen suppositories; 2, ibuprofen: ibuprofen class of antipyretic drugs are mainly suitable for infants and children over 6 months of age, there are also suppositories, if the child is accompanied by obvious nausea, vomiting or difficulty taking oral medication, you can also choose to use ibuprofen suppositories for children; 3, Nimesulide: Nimesulide The children’s fever is also a child antipyretic drug, but it is suitable for children over 12 years old, children under 12 years old is prohibited to use; 4, Chinese medicine antipyretic drugs: children can use antipyretic drugs and Chinese medicine antipyretic drugs, such as pediatric Chai Gui antipyretic particles, pediatric black beetle fever particles, Lianhua Qing Fei granules. The effect of Chinese medicine is relatively milder, but it is best to choose the corresponding Chinese medicine under the guidance of an herbalist or Chinese pharmacist. If the antipyretic medicine is ineffective, it needs to be replaced by western antipyretic medicine in a timely manner so that the persistent high fever does not subside, leading to febrile convulsions in children.