The treatment of acute lymphocytic leukemia is mainly chemotherapy and bone marrow transplantation, and the method used and the effectiveness of the treatment depends mainly on the presence of risk factors. In general, risk factors for acute gonorrhea include age >10 years, presence of adverse chromosomal abnormalities (Ph’), high white blood cells >100 at initial diagnosis, insensitivity to prednisone testing, and type of lymphocytes, among others. If more risk factors are present and chemotherapy does not guarantee long-term remission, early bone marrow transplantation is currently advocated, and chemotherapy may be preferred if there are no risk factors. Even for high-risk acute lymphoma, the choice of bone marrow transplantation requires several conditions to be considered, as transplantation requires good economic conditions, and the risk of bone marrow transplantation is high, with the risk of failure, risk of relapse, risk of transplantation-related death, and risk of GVHD all being fully considered.