Dapoxetine is a drug for premature ejaculation, which has an effect on the prolongation of sexual intercourse, which takes about 1-2 hours, but the prolongation time varies according to each person’s sensitivity to the drug. Dapoxetine is a highly selective 5-hydroxytryptamine reuptake inhibitor, mainly for premature ejaculation caused by overly sensitive male psychological factors or abnormally increased secretion of 5-hydroxytryptamine and dopamine in the brain. It is usually taken 1-3 hours before sex and usually works for 1-2 hours, but due to the different persistence time of individual sex, most of them can be delayed for more than 10 minutes. During the medication period, psychotherapy and behavioral therapy should also be carried out, regular rest and relaxation, do not have too much pressure and burden, and physical exercise to maximize its effectiveness. In addition, taking dapoxetine may cause nausea, vomiting, dizziness and other adverse reactions, do not worry too much, generally after the effect of the drug will disappear on its own.