Can colorectal cancer be cured? How long can a patient live with colorectal cancer? It mainly depends on the patient’s specific condition, the patient’s physical quality and whether the patient can be treated effectively, whether the patient has a good mentality, whether the patient has received good care, etc. Can colorectal cancer be cured? Let’s see how the following experts introduce: The treatment of colorectal cancer advocates a comprehensive treatment plan mainly based on surgical resection. Most primary tumors can be radically resected, and the principle is to remove the intestinal segment where the tumor is located (including the proximal 10cm and distal 7cm, the corresponding mesentery and the lymph nodes). If radical surgery cannot be performed, palliative resection can still be performed to relieve symptoms and improve patients’ quality of life. The 5-year survival rate after surgery is closely related to the pathological stage of colorectal cancer, and the 5-year survival rate after surgery for early-stage colorectal cancer can reach more than 80%, but only about 40% for mid- to late-stage cancer. The combined treatment plan includes chemotherapy with 5-fluorouracil precipitated as the first choice and radiotherapy and thermotherapy, etc. The efficiency of 5-fluorouracil for colorectal cancer is close to 20%, and the combined use of mf (5-fluorouracil + methylcyclic nitrosourea) and mof (mitomycin + 5-fluorouracil + vincristine), etc., the efficiency can reach 30%. Recently, Southern Hospital has proposed high-dose 5-fluorouracil intraperitoneal thermostatic infusion chemotherapy, which can improve the survival rate of postoperative colorectal cancer. Radiotherapy is mostly applied to rectum and lower sigmoid colon with fixed location, and it is effective for highly differentiated adenocarcinoma with diameter <5cm. Radiotherapy is mostly administered preoperatively, but can also be administered intraoperatively and postoperatively. Intraluminal radiotherapy has the advantages of good effect and less side effects, and the dose is about 10,000-15,000 cgy for 4-6 weeks. The remission rate of local symptoms can reach 50% to 85% after patients receive treatment, and generally can achieve remission for 6 to 8 months. The opinions of heat therapy as a routine adjuvant treatment for colorectal cancer are not uniform, but some studies have shown that preoperative heat therapy can improve the surgical resection rate of mid- to late-stage colorectal cancer. In addition, electrocoagulation therapy, cryotherapy, microwave therapy and photosensitization therapy also receive certain effects. It is worth mentioning that colorectal cancer is a systemic and chronic wasting disease. In order to improve the tolerance to chemotherapy and radiotherapy and to complete the comprehensive treatment successfully, it is an important part of the comprehensive treatment to strengthen the supportive treatment, improve the nutritional status of patients, enhance the physical fitness and thus improve the immune function. Biological immunotherapy is the research direction of colorectal cancer treatment, for example, in addition to the traditional immunotherapy and immune vaccine treatment using agents with immune function, the simple preparation of membrane antigen wrapped in lipid around the surgically resected specimen of colorectal cancer patients has been started to be injected into the body of colorectal cancer patients, which can specifically activate immune active cells in the patient's body to kill the remaining cancer cells and improve the 5-year survival rate. The application of monoclonal antibody-coupled drugs, toxins or radionuclides to colorectal cancer-associated antigens for guided chemotherapy and radiotherapy has made great progress in animal experiments, and secondary immunotherapy with lak cells and tumor-infiltrating lymphocytes has been tried in the clinic. In addition, the use of gene transfection to introduce cytokines, anti-cancer genes, and heterologously expressed antigens into tumor cells to kill or induce cancer cells has provided a new avenue for the treatment of colorectal cancer.