In ophthalmology clinics, we often see children who are seen for frequent blinking and parents complain: Why do the eye drops not work after so long? First of all, we need to know that the normal blink is an eyelid nerve reflex that has a physiological significance: it is a protective measure to lubricate the cornea to maintain the normal function of the eye surface and to prevent foreign body intrusion. The normal transient does not exceed 15 times per minute. The concept of “frequent” eye transients is not uniformly defined, but is generally considered to be “frequent” within 5 seconds, with one to several transients within 3 seconds. Frequent eye transients in children are common and frequent in ophthalmology clinics, and because the cerebral cortex is not well developed in childhood, it often shows “overreactivity”, and psychological factors are very disturbing. Therefore, parents must pay attention to it. The following is a list of the causes of frequent transients in children, combined with the many clinical cases I have encountered: (1) Ocular surface and ocular appendage disorders Conjunctivitis or conjunctival stones, entropion, chalazion, and punctate keratitis are among the children seen in outpatient clinics. The conjunctiva is directly connected to the lid and inflammation or infection can cause immune tissue to accumulate and form follicles and papillae. In addition, when chronic inflammation of the conjunctiva is present, inflammatory exudate is deposited in the lid conjunctival glandular ducts or in the epithelial depressions of the conjunctiva, and tangible material coagulates, which can appear as small yellowish-white punctate conjunctival stones in the lid conjunctiva . Both conjunctivitis and conjunctival stones can irritate the ocular surface causing frequent transients. The cornea is rich in sensory nerve endings, so corneal perception is very sensitive. The sensitivity of corneal perception in children is higher than that of adults. Therefore, the anatomical characteristics of the conjunctiva and cornea in children lead to the susceptibility of conjunctival and corneal lesions, which leads to the susceptibility of children to frequent transients. (2) Video terminal syndrome With the change of modern life style and work style and the progress of society, the videodisplayterminal (VDT) operation is widely used and VDT syndrome is becoming more and more common, the manifestation of VDT syndrome in children is more obvious than in adults, and the main manifestation is frequent transient eyes, because the computer consists of small fluorescent dots VDT syndrome is more common in children than in adults, and is mainly manifested by frequent transients, because computers are composed of small fluorescent dots, and the video player’s eyes move frequently between the video screen, the file and the keyboard, and the eyes are constantly mediating between the viewpoints and the visual distance to ensure clear vision. Too long, the eye muscle will be too fatigued, resulting in an increase in the number of transients; computer fluorescent screen emitted ultraviolet, infrared, rays, ultra-low frequency, etc. will also produce strong stimulation of the eyes, causing eye dryness, fatigue, double vision, blurred vision and even head and neck pain and other problems, coupled with the flicker, reflection and dazzle of the video screen, resulting in the trigeminal nerve or optic nerve is affected; childhood due to the cerebral cortex is not well developed, visual In childhood, due to the imperfect development of the cerebral cortex and the incomplete development of vision, watching TV for a long time can cause hyperexcitability of the balance inhibition of the higher visual center, causing a reflexive defense action. (3) Refractive abnormalities are characterized by refractive error, which is a state of non-rectal vision in which parallel rays entering the eye without adjustment cannot become a clear image on the retina after refraction, which is commonly referred to as refractive error. The reason is that the optical focal point of the farsighted eye is behind the retina, so the image on the retina is blurred, and in order to see distant objects clearly, the focal point behind the retina has to be moved to the retina using the adjustment force, and when looking at near objects, part of the adjustment force has to be increased, so the farsighted eye is often in the state of over-adjustment and over-strength of the collection, which is prone to visual fatigue, internal strabismus, itching, dryness and discomfort, Myopic children are prone to visual fatigue, internal strabismus, itchy eyes, dryness and discomfort, so they change their blurred and fatigued state as much as possible by frequent transients. Narrowing the lid fissure to a pinhole or slit to make the retina imaging clear for a long time causes spasmodic contraction of the orbicularis oculi muscle. And the affected child reflexively takes transient movements in order to relieve eye discomfort. (4) Instability of the tear film The tear film is the liquid film covered by tears on the surface of the cornea and bulbar conjunctiva, and is the basis for maintaining the normal structure and function of the epithelium on the ocular surface. There are many causes of tear film instability in children: ocular surface and ocular appendage disorders, vitamin A deficiency, the prevalence of video terminals, improper medical treatment, poor transient habits, close contact with pets and toys, systemic immune diseases, and allergic diseases can cause tear film instability. When the tear film is abnormal, the child may experience burning, itching, foreign body sensation, and pain and dryness, all of which can cause an increase in transient eye movements. (5) Allergic eye disease Clinically, allergic conjunctivitis and allergic blepharitis are common. The main symptoms are redness, itching, increased discharge, and frequent blinking. These children also have other systemic allergic diseases, such as allergic rhinitis, asthma, and dermatitis. (6) Tourette’s syndrome Tourette’s syndrome is a neuropsychiatric disorder that occurs in childhood. In the eyes, it mainly manifests as frequent or involuntary blinking, accompanied by forehead wrinkling, nasal aspiration, pouting, distraction, hyperactivity, and poor self-control. Neurological and psychological factors are often important in aggravating or recurring blinks. The transient reflex can detect not only lesions of the trigeminal and facial nerves, but also functional disorders of the brainstem. Children with suspected transient reflexes who have failed ophthalmic treatment should be seen by a pediatric neurologist to rule out possible neurological disorders. (7) Others Children with long-term picky eating and irregular diet may have insufficient or unbalanced nutritional intake, resulting in nutritional deficiencies in the body, especially vitamins (B2, A) and trace elements (zinc deficiency, iron deficiency), and elevated lead can cause increased neuromuscular stress and neurological dysfunction, leading to frequent transient eyes. In addition, in clinical work, we also encounter frequent transient eyes due to intestinal roundworm disease, so we should perform routine fecal worm egg examination, and those with positive results should be dewormed.