Hypothyroidism can have no clinical symptoms. It can also present with weight gain, edema, sluggish facial expressions, slow speech, fear of cold, constipation, thinning hair, dry and rough skin, fatigue and weakness, inactive thinking, unresponsiveness, memory loss, slow movement, drowsiness, amnesia, numbness of hands and feet, progressive personality changes, some manifestations of depression, and possibly significant psychosis. Hypothyroid women often have excessive menstruation. After iodine-131 treatment, you should go to the hospital regularly for blood tests to determine if you have hypothyroidism so that you can be treated promptly.