Black and purple lips may be related to physiological factors, poisoning, rheumatic heart disease, chronic obstructive pulmonary disease and other factors. Different causes are treated in different ways, as follows: 1. Physiological factors: if the organism is at high altitude, cold and other environments for a long time, it will lead to poor blood circulation and black and purple lips. For this situation, it is recommended to leave the oxygen-deficient, cold environment in time. 2. Poisoning: Toxic substances enter the patient’s body, leading to abnormalities in the nervous system and other functions, resulting in black and purple lips and hot skin. For this situation, it is recommended to go to the hospital in time, such as vomiting, gastric lavage and so on. 3. Rheumatic heart disease: heart failure, causing blood circulation to slow down, insufficient blood supply, the symptoms of black and purple lips. In this case, it is recommended to take oral medication (e.g. penicillin, warfarin, etc.) under the guidance of a doctor or undergo surgical treatment. 4. Chronic obstructive pulmonary disease (COPD): COPD patients have low hemoglobin oxygen content in the blood, which in turn causes hypoxemia, resulting in symptoms such as dyspnea and black and purple lips. For this situation, it is recommended to take oral aminobromine syrup, orange red phlegm cough liquid, etc., and at the same time with the nebulized inhalation, such as budesonide nebulized liquid, salbutamol nebulized liquid, etc.. In addition to black lips, if accompanied by other uncomfortable symptoms, it is recommended to go to the hospital in a timely manner, improve the examination to determine the cause of the disease, and then follow the doctor’s instructions for treatment.