H. pylori infection does not usually result in obvious darkening of the lips, but darkening of the upper lip may occur if loss of appetite, diarrhea, etc. occur. Early after H. pylori infection can have no obvious clinical symptoms, with the development of the disease, some patients will appear stomach discomfort, including belching (burping), bloating, acid reflux, heartburn, loss of appetite, intermittent abdominal discomfort, indigestion and other symptoms, but generally does not cause black lips, if food loss, diarrhea, and other more serious people may cause black mouth. The causes of black lips may include hyperpigmentation, nervousness, smoking, chronic obstructive pulmonary disease, pulmonary heart disease, liver insufficiency, poisoning, etc., daily attention should be paid to pay close attention to their own health changes. Do not adapt to the timely consultation, follow the doctor’s instructions for treatment.