There are three major symptoms of bladder irritation, urinary frequency, urinary urgency, and urinary pain. A normal person urinates about 4-6 times a day and 0-1 times at night. If the number of nighttime urination is greater than 2 times, or the number of daytime urination is greater than 6 times, it is called frequent urination. Painful urination is a painful sensation in the bladder area or urethra during urination, usually of a burning or stinging nature. There are a number of diseases that cause bladder irritation: 1, the most common is urinary tract infection, including bacteria, fungi, viruses, mycoplasma, chlamydia, etc., the most common is acute cystitis; 2, urethral syndrome, and mental factors have a certain relationship, mostly seen in women. Women exclude the signs of urethral irritation due to organic lesions, mostly caused by overactive bladder syndrome. In addition, stones and tumors of the urinary system can also lead to the appearance of bladder irritation signs.