Forearm osteo-fascial compartment syndrome is an extremely serious complication. If a patient develops severe pain in the forearm, impaired finger movement, sensory disturbances, pale/cyanotic skin and increased skin surface tension after the fracture has been repositioned and fixed, the patient should be alerted to forearm osteo-fascial compartment syndrome, which may lead to limb disability or even amputation if not treated in time. In all cases of forearm osteo-fascial compartment syndrome, external fixation should be removed immediately, and if blood flow does not improve after removal of fixation, deep fasciotomy and myotomy should be performed immediately.