Dry eyes and dry mouth may be caused by diabetes, dry syndrome and other factors, mainly for drug treatment, the cause of different drugs are different, including hypoglycemic drugs, immunosuppressants and artificial tears. 1. Diabetes: For dry eyes and dry mouth caused by diabetes, oral hypoglycemic drugs should be taken for treatment, such as metformin, pioglitazone, and insulin injection should be taken when the blood glucose is too high to avoid repeated increase in blood glucose, and the diet should be adjusted to avoid eating food with high sugar content. 2. Dry syndrome: When dry syndrome is identified, drug treatment can be carried out, using sodium vitrate eye drops, polyvinyl alcohol eye drops, etc., to alleviate the symptoms of dry eyes, and can also be used in conjunction with the use of immunosuppressants for treatment, such as methotrexate, cyclophosphamide, etc., which can inhibit abnormal immune response and control the development of the disease. In order to avoid serious adverse reactions, any medication should be used in accordance with the doctor’s instructions, and reasonable rest should be taken to reduce the time of eye use.