The adverse reactions in the instructions of busulfan anti-inflammatory oral solution are not yet clear, and a review of the literature revealed that the adverse reactions that occurred in patients in the study of busulfan anti-inflammatory oral solution for the treatment of acute suppurative tonsillitis were mostly manifested as diarrhea, vomiting and temperature fluctuations. During the treatment of plaque gingivitis, two patients had abnormal taste reactions, which returned to normal after discontinuation of the drug.In 2018, the State Drug Administration revised the adverse reactions of busulfan anti-inflammatory tablets (capsules), and since the oral solution has the same ingredients as the tablets and capsules, the adverse reactions of busulfan oral solution mainly include digestive system, skin system, and nervous system The adverse reactions of oral solution include digestive system, skin system and nervous system. The adverse reactions of digestive system include nausea, vomiting, abdominal distension, abdominal pain, diarrhea, loss of appetite, etc. The adverse reactions of skin system are allergic reactions such as rash, itching, etc. The adverse reactions of nervous system include weakness, dizziness, abnormal sensation, etc. In addition, because the four herbs in the composition of Pu Di Lan Anti-inflammatory Oral Solution are cold in nature, pregnant women need to use it with caution; patients with abdominal pain, warmth, diarrhea and other symptoms of spleen and stomach deficiency may appear pale and sweating after taking it, resulting in aggravation of the condition, and need to use it with caution; women during menstruation also need to use it with caution to avoid the symptoms of reduced menstrual flow and dysmenorrhea after using it.