Male penis root sides are very painful, and accompanied by severe hematuria, the main consideration with urinary tract infection, urinary stones, urinary tract adjacent organs diseases and other factors. 1. Urinary tract infection: such as urethritis and other diseases, can lead to the affected area red, swollen, congested, stimulated by inflammation, can appear at the root of the penis on both sides of the ureteral pain, painful urination, urinary frequency and hematuria and other symptoms. 2. urinary stones: such as bladder stones, kidney stones, etc., some small stones can enter the ureter with the urine, after entering the ureter may scratch the ureteral mucosa, or the formation of obstruction, and then the root of the penis on both sides of the pain and hematuria and other symptoms. 3. Diseases of the neighboring organs of the urinary tract: such as acute and chronic prostatitis, which can also lead to the emergence of pain at the base of the penis, hematuria and other uncomfortable symptoms. The above symptoms may also be related to other pathological factors, it is recommended to consult a doctor to confirm the diagnosis, and standardized treatment under the guidance of the doctor.