Application of triethanolamine is generally harmless to the skin in moderate amounts; excessive use or prolonged exposure may cause damage to the skin. After application of triethanolamine, the skin may experience mild, transient tingling and itching, and in a relatively small number of people, allergy may occur. Triethanolamine mainly increases the blood flow rate to the skin and speeds up the outflow of exudate, and also promotes fibroblast proliferation, as well as collagen synthesis, and can be used to treat erythema that occurs after radiation therapy, as well as first- and second-degree burns and skin wounds that have not yet become infected. When patients develop secondary erythema after receiving radiotherapy, triethanolamine can be applied to the skin and gently massaged to promote absorption. For second-degree burns and partial skin wounds, after cleaning the wound, triethanolamine can be applied repeatedly to ensure adequate wound medication, followed by a wet gauze dressing. In contrast, first-degree burns can be applied with less medication compared to second-degree burns. If these symptoms are severe or the burn area is relatively large, you should seek medical attention promptly. When using triethanolamine, it is important to pay attention to the concentration and content because it has alkaline within it, and if too much is used it may cause damage to the skin, leading to itching, inflammation, and allergy. Also, if long-term exposure to triethanolamine is required, one should be well protected and wear gloves to avoid skin damage from long-term exposure. When patients have bleeding wounds, infected wounds, or are allergic to triethanolamine, it is prohibited to apply triethanolamine to the skin. In addition, women who are pregnant or breastfeeding should use this drug with caution and it is best to consult a doctor first.