The early stage of vitiligo generally refers to the first three months when vitiligo is discovered, vitiligo belongs to autoimmune disease, for vitiligo, early detection and early treatment is the key to control the disease and restore the white spots. In the early stage of vitiligo, small doses of hormones are generally used, such as once a month injection of compound betamethasone or about 10-20mg of prednisone taken orally every day to control the development of vitiligo. The small dose of hormone generally need to continue to use about three months, if there is a contraindication to the use of hormone, you can also use immunomodulators, such as compound glycyrrhizin, white peony total glucoside or transfer factor to control vitiligo, the use of time is generally three months. Generally also have to also with topical medication, morning generally choose medium to strong topical hormone, such as mometasone furoate, halometasone. In the evening choose non-hormonal drugs, such as tacrolimus, pimecrolimus, combined with internal drugs, to control the development of vitiligo. After using small doses of hormones or immunomodulators to control vitiligo for a full month, you can combine with doing phototherapy, commonly 308nm excimer laser, long wave ultraviolet UVA, medium wave ultraviolet UVB. depending on the type of phototherapy and the onset site, the white spots are usually irradiated with 1-3 times a week treatment. Phototherapy can stimulate the melanocytes around the white spot to grow towards the white spot and also stimulate the residual melanocytes inside the white spot to appear as pigment islands, which can be used to restore the white spot in these two ways. For leukoplakia, the earlier the treatment, the higher the success rate. The success rate of recovery through phototherapy is particularly high in early small areas, so it is recommended that patients with leukoplakia be treated promptly at an early stage.