Uric acid 435 μmol/L is not normal. Non-same day 2 fasting blood uric acid > 420 μmol/L is called hyperuricemia. If hyperuricemia remains untreated, it may cause gouty arthritis, gouty nephropathy, and other adverse effects. Uric acid 435μmol/L is above the normal range and can be controlled by general treatment and, if necessary, medication. General treatment mainly involves adjusting lifestyle, controlling total calorie intake, limiting alcohol consumption, reducing intake of high-purine foods such as animal offal, seafood, mushrooms, etc., and drinking plenty of water every day to increase uric acid excretion. In terms of medication, if necessary, patients with high blood uric acid can use allopurinol, febuxostat, benzbromarone and other drugs to reduce uric acid levels, drugs should be used under the guidance of a doctor. Patients with high blood uric acid are advised to go to the rheumatology and immunology departments of regular hospitals for detailed consultation.