The advantages and disadvantages of puncture are as follows: 1. Advantages: Puncture can make a clear diagnosis, and pathological diagnosis is the gold standard. At present, ultrasound is often very accurate and can detect very small nodules, and there may be some difficulties on puncture for very small nodules. In pathological diagnosis, malignant tumors may also be undiagnosed, and it is possible that the puncture diagnosis may suspect malignant tumors, but the final surgical results are inconsistent, but of course the possibility of inconsistency is low. The puncture site is very small, similar to a needle hole in a syringe, but the thyroid gland is rich in blood supply, so there is a risk of bleeding or infection during the puncture.