Blood uric acid 450 μmol / L has exceeded the normal level, the causes of elevated blood uric acid mainly include dietary habits, related diseases, excessive production or reduced excretion of uric acid, drugs and other factors.
1. Dietary habits: Long-term consumption of high-purine diets may lead to elevated blood uric acid, such as animal offal, seafood, thick soup, and drinking a lot of beer.
2. Related diseases: blood system diseases such as multiple bone marrow, lymphoma and leukemia may lead to elevated blood uric acid.
3. Excessive production or reduced excretion of uric acid: Uric acid enzyme deficiency and defective genes related to uric acid transport may lead to congenital excessive production of uric acid. Kidney is the main organ to excrete uric acid, glomerular disease, tubular disease may lead to reduced uric acid excretion, causing elevated blood uric acid.
4. Drug factors: long-term use of aspirin, hydrochlorothiazide, furosemide, theophylline tablets, human insulin and other drugs may lead to elevated blood uric acid.
Blood uric acid 450μmol / L may also be related to other factors, it is recommended that patients promptly to the regular hospital endocrinology, rheumatology and immunology departments and other related departments for detailed consultation.