(a) Infections and allergies in children with chronic cough are mostly manifested as pan-infections and immune (immune) inflammatory reactions, with parents often complaining of “recurrent colds; low immunity” and specialists diagnosing “chronic recurrent rhinitis, laryngitis, peribronchitis, pneumonia, mycoplasma infection, cough variant asthma CVA”. Pan-infection and anti-inflammatory reactions are causally related and are mostly caused by internal/external factors (diet or feeding, environment) that disrupt the body’s own microbiota; in case of prolongation, a systemic disruption of the neurological/endocrine/immune network regulation occurs. It requires dynamic and careful observation of local respiratory symptoms and overall systemic manifestations, careful analysis to detect them, and doctor-patient communication. Laboratory tests, including multiple high-tech molecular biology assays (e.g., allergens, inflammatory immune indicators), chest CT, and pulmonary function are only auxiliary reference roles. (B) Current common misconceptions and problems: 1, parents (children): “anxiety mentality, fear of asthma, pneumonia, “root of the disease”, the pursuit of a definitive diagnosis of the most famous doctors, looking for special drugs; lack of overall dynamic observation of the child to think about the analysis; ignore the role of family atmosphere and environmental factors. 2, the doctor: simple mechanical blood routine, chest X-ray under the diagnosis; simple or excessive reliance on drugs; 3, specific performance: (1) infants simple type diagnosis of pneumonia peri-bronchiolitis long-term repeated antibiotics, diagnosis of asthma single long-term nebulized aspiration led to oral upper airway phyla disorder; (2) children complex type: ignore the mind and body (psychological, behavioral, habit) comprehensive factors, one-sided to mycoplasma antibody (the current quantitative measured antibodies include IgG and IgM) as evidence antibiotic treatment. (3) My thoughts and response ideas 1. Improve the traditional concept and classification of infection, inflammation and allergy; avoid mechanical static “infection/allergy, differential diagnosis and treatment”. 2. Refine the integrated intervention, medication (according to the person/time/place; physiological/psychological): alternate synergistic regulation of pan-infection/inflammation-free reactions; 3. Explore the Internet medical intervention model: popularization of science, exchange among mothers, doctor participation guidance, continuous refinement of symptom observation and doctor-patient communication.