There is no definitive research on a diabetes vaccine, it is still unknown. Diabetes is not a single disease, it is a syndrome caused by a complex etiology, the result of a combination of factors including environmental and genetic factors. Type 1 diabetes is an absolute lack of insulin caused by the destruction of pancreatic β-cells and often requires lifelong insulin therapy. 2. Type 2 diabetes mellitus is mainly caused by insulin resistance and relative lack of insulin secretion, and is mostly seen in obese people. Treatment such as lowering glucose, lowering blood pressure, regulating blood lipids and improving body weight should be carried out according to the individual symptoms of patients. 3. Special type of diabetes mellitus is similar to type 2 diabetes mellitus in clinical symptoms, but due to the causes of the disease, the specific treatment needs to be based on the cause of the disease, symptomatic treatment. 4. Gestational diabetes mellitus refers to diabetes mellitus that occurs or is diagnosed during pregnancy in women with normal glucose metabolism or underlying abnormal glucose tolerance before pregnancy. Diet and exercise therapy are generally recommended, and insulin therapy is recommended if blood glucose control is poor. With the advancement of biomedical science and technology, we expect that there will be more medications for diabetes used in the clinic, and it is important to seek medical attention if you are not feeling well.