Age-related macular degeneration, is the main cause of vision loss in patients over the age of 50. The macula is located in the central part of the retina at the bottom of the eye and is covered with optic vertebral (photoreceptor) cells, thus enabling us to see the details and colors of objects clearly and is the area of sharpest vision. In daily life, study and work: reading books, reading newspapers, driving, reading the time, recognizing facial features, etc. all rely on the macula area. Once the macula is damaged, a person’s vision is severely reduced, with distorted vision and a black spot in the center of the visual field. Compared with cataracts and other surgically recoverable blinding eye diseases, the consequences of macular degeneration are more serious, causing permanent and irreversible loss of visual function. The cause of macular degeneration is unknown, but numerous studies have shown that it is associated with age, genetic environment, nutrition, sunlight exposure, smoking and other factors. Patients with macular degeneration often have blurred vision and other symptoms in the early stage, but many middle-aged and elderly people may mistake it for natural changes caused by aging or “presbyopia” and delay seeking medical attention, which eventually causes serious damage to vision and even blindness. If timely consultation is made, it is possible to reduce or delay the vision loss caused by wet macular degeneration. Clinically, it can be divided into two types: dry and wet. A simple understanding: dry is macular degeneration without bleeding, while wet is macular degeneration with neovascularization that causes bleeding. 85% of patients belong to dry macular degeneration. These patients may have no symptoms at all in the early stage, and even if they have, they only have slight blurred vision and visual distortion, which are easily ignored. In contrast, wet macular degeneration will form new blood vessels in the macular area, which are too fragile and can easily lead to bleeding. Once the bleeding becomes a scar, it is difficult to treat and may eventually lead to blindness. Therefore, it is recommended that: middle-aged and elderly people over 50 years old (especially those with history of diabetes, hypertension and hyperlipidemia) should have regular health checkups and regular eye examinations, which is an effective way to detect macular degeneration at an early stage. If you have vision loss, distortion, or central visual field defect, you should go to the ophthalmology department as soon as possible for funduscopy, optical coherence tomography and fundus angiography to confirm the diagnosis of age-related macular degeneration.