Meningioma and chordoma are the two main types of tumors in the work of neurosurgeons. Although they are benign tumors, they are prone to recurrence because they are not cleanly cut, especially chordoma. The chordoma is a developing embryonic tissue that gradually degenerates during development, with the upper end distributed in the pterygoid and occipital bones at the base of the skull and the lower end in the central part of the sacrococcygeal region. At 3 months of age, the notochord begins to degenerate and disappear, with the upper and lower ends gradually degenerating and fusing with the cranial base and sacrococcygeal bones, while the middle notochord degenerates into the nucleus pulposus of the intervertebral disc. If the upper and lower chordal cords do not completely degenerate and disappear, they become tumors, known as chordomas. Chordoma is located deep, mostly in the midline skull base. The pterygoid saddle area, slope and extended cervical junction area are the sites of skull base chordoma. Chordoma in the pterygoid saddle area can be operated endoscopically through the pterygoid sinus, and if the chordoma invades the cavernous sinus, total surgical resection is almost impossible, while in the slope and extended cervical junction area, chordoma must be performed in the gap of the cranial nerve, and total tumor resection is also difficult to achieve. That is, for chordoma, total surgical resection is difficult to achieve. This is what we often call chordoma as a benign tumor with malignant growth. Surgery, recurrence, re-surgery, and still recurrence, even when supplemented with radiation therapy such as CyberKnife, still cannot avoid tumor recurrence. I have seen patients with chordoma who have undergone surgery in four of the country’s leading neurosurgical units in the clinic, and even with the big name professors, recurrence of chordoma cannot be avoided. Of course, the time to recurrence varies with different pathological types of chordoma (general, chondrogenic, mesenchymal), but no matter how much surgery is performed, it will still recur.