Uneven fatty liver can be relieved and treated by general treatment such as diet adjustment and exercise, medication such as orlistat and surgery such as liver transplantation. 1.General treatment: (1) Dietary adjustment: moderate control of dietary calorie intake, balanced diet with appropriate fat and carbohydrates, limiting sugary beverages, pastries and deep-processed foods such as cookies and ham sausages. Increase the intake of whole grain foods and dietary fiber, such as corn, oats, barley, etc.. (2) Reasonable exercise: Avoid sedentary activities, and insist on moderate aerobic exercise such as big steps and brisk walking to accelerate blood circulation and metabolism. 2. Medication: (1) Orlistat: suitable for adults with BMI ≥30kg/m² and adults with BMI ≥27kg/m² and comorbidities such as hypertension, type 2 diabetes mellitus and dyslipidemia. (2) Angiotensin II receptor antagonists: such as valsartan, irbesartan, etc., are suitable for the treatment of hypertension in patients with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. 3. Surgical treatment: such as liver transplantation surgery, etc., which can relieve and treat the symptoms of uneven fatty liver disease such as nausea, vomiting and fatigue to a certain extent. It is recommended to consult a doctor in time to get a clear diagnosis and targeted treatment for uneven fatty liver. In addition, all of the above medications should be taken under the guidance of a doctor and should not be taken without authorization.